Last week gave us several curveball games that changed the season. This week brings even more fun showdowns, with Notre Dame going to BYU, Ohio State at Indiana, Alabama at Tennessee, and Missouri at Ole Miss. Here are this week’s CFN Expert Picks for the biggest games.
Jump to each game
Del at MTSU | FIU at Jax St | WKU at SHSU
ECU at UAB | Mem at Tulane | Wash at Purdue
OSU at IU | Florida at Texas | Miss St at LSU
NW at Mich St | Auburn at UGA | Bama at Tenn
Mizz at Ole Miss | ASU at TTech | PSU at Mich
FSU at Miami | ND at BYU | Wisconsin at UCLA
UK at OU | Ok St at Houston | Utah at Colorado
Nebraska at Oregon | Results So Far
* means will win, but not cover
Delaware at Middle Tennessee
Game Preview and Prediction
Consensus Line: Delaware -2.5
Big Game Ben: Delaware
Andre Cherry: Middle Tennessee
Riley Donald: Delaware
E: Delaware
Pete Fiutak: Middle Tennessee
John Kennedy: Middle Tennessee
Jackson Langendorf: Delaware
Andrew Margolick: COMING
Jake Margolick: Middle Tennessee
Doug Millen: Delaware
Connor O’Gara: Delaware
Johnny Rosenstein: Middle Tennessee
Nick Shepkowski: Middle Tennessee
Clucko the Chicken: Delaware
Consensus Pick: Delaware
FIU at Jacksonville State
Game Preview and Prediction
Consensus Line: Jacksonville State -2.5
Big Game Ben: Jacksonville State
Andre Cherry: Jacksonville State
Riley Donald: FIU
E: Jacksonville State
Pete Fiutak: Jacksonville State
John Kennedy: Jacksonville State
Jackson Langendorf: FIU
Andrew Margolick: COMING
Jake Margolick: Jacksonville State
Doug Millen: Jacksonville State*
Connor O’Gara: Jacksonville State*
Johnny Rosenstein: Jacksonville State
Nick Shepkowski: Jacksonville State
Clucko the Chicken: FIU
Consensus Pick: Jacksonville State
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Western Kentucky at Sam Houston
Game Preview and Prediction
Consensus Line: Western Kentucky -1.5
Big Game Ben: Sam Houston
Andre Cherry: Western Kentucky
Riley Donald: Western Kentucky
E: Western Kentucky
Pete Fiutak: Western Kentucky
John Kennedy: Western Kentucky
Jackson Langendorf: Sam Houston
Andrew Margolick: COMING
Jake Margolick: Western Kentucky
Doug Millen: Western Kentucky
Connor O’Gara: Western Kentucky
Johnny Rosenstein: Western Kentucky
Nick Shepkowski: Sam Houston
Clucko the Chicken: Sam Houston
Consensus Pick: Western Kentucky
East Carolina at UAB
Game Preview and Prediction
Consensus Line: East Carolina -4.5
Big Game Ben: East Carolina
Andre Cherry: East Carolina*
Riley Donald: East Carolina
E: East Carolina
Pete Fiutak: UAB
John Kennedy: East Carolina
Jackson Langendorf: UAB
Andrew Margolick: COMING
Jake Margolick: East Carolina
Doug Millen: East Carolina*
Connor O’Gara: UAB
Johnny Rosenstein: East Carolina
Nick Shepkowski: East Carolina
Clucko the Chicken: East Carolina
Consensus Pick: East Carolina
Memphis at Tulane
Game Preview and Prediction
Consensus Line: Memphis -7.5
Big Game Ben: Memphis*
Andre Cherry: Memphis
Riley Donald: Memphis
E: Memphis*
Pete Fiutak: Memphis
John Kennedy: Memphis
Jackson Langendorf: Memphis
Andrew Margolick: COMING
Jake Margolick: Memphis
Doug Millen: Memphis*
Connor O’Gara: Memphis*
Johnny Rosenstein: Memphis*
Nick Shepkowski: Memphis
Clucko the Chicken: Tulane
Consensus Pick: Memphis
Washington at Purdue
Game Preview and Prediction
Consensus Line: Purdue -3.5
Big Game Ben: Purdue
Andre Cherry: Washington
Riley Donald: Purdue
E: Washington
Pete Fiutak: Purdue
John Kennedy: Purdue
Jackson Langendorf: Purdue
Andrew Margolick: COMING
Jake Margolick: Purdue
Doug Millen: Purdue*
Connor O’Gara: Purdue
Johnny Rosenstein: Purdue*
Nick Shepkowski: Purdue
Clucko the Chicken: Washington
Consensus Pick: Purdue
Ohio State at Indiana
Oct 10, 2026; Columbus, Ohio, USA; Ohio State Buckeyes head coach Ryan Day greets defensive end Kenyatta Jackson Jr. (2) before the game against the Maryland Terrapins at Ohio Stadium. Mandatory Credit: Joseph Maiorana-Imagn Images
Game Preview and Prediction
Consensus Line: Ohio State -3.5
Big Game Ben: Ohio State
Andre Cherry: Ohio State
Riley Donald: Ohio State
E: Ohio State
Pete Fiutak: Ohio State
John Kennedy: Ohio State
Jackson Langendorf: Ohio State
Andrew Margolick: COMING
Jake Margolick: Ohio State
Doug Millen: Ohio State*
Connor O’Gara: Ohio State
Johnny Rosenstein: Ohio State
Nick Shepkowski: Ohio State
Clucko the Chicken: Indiana
Consensus Pick: Ohio State
Florida at Texas
Game Preview and Prediction
Consensus Line: Texas -10.5
Big Game Ben: Texas*
Andre Cherry: Texas*
Riley Donald: Texas*
E: Texas
Pete Fiutak: Texas*
John Kennedy: Texas
Jackson Langendorf: Texas
Andrew Margolick: COMING
Jake Margolick: Texas*
Doug Millen: Texas*
Connor O’Gara: Texas*
Johnny Rosenstein: Texas*
Nick Shepkowski: Texas
Clucko the Chicken: Texas
Consensus Pick: Texas*
Mississippi State at LSU
Game Preview and Prediction
Consensus Line: LSU -14.5
Big Game Ben: LSU*
Andre Cherry: LSU*
Riley Donald: LSU*
E: LSU*
Pete Fiutak: LSU
John Kennedy: LSU*
Jackson Langendorf: LSU
Andrew Margolick: COMING
Jake Margolick: LSU*
Doug Millen: LSU
Connor O’Gara: LSU
Johnny Rosenstein: LSU*
Nick Shepkowski: LSU
Clucko the Chicken: Mississippi State
Consensus Pick: LSU*
Northwestern at Michigan State
Game Preview and Prediction
Consensus Line: Northwestern -7.5
Big Game Ben: Northwestern
Andre Cherry: Northwestern*
Riley Donald: Northwestern
E: Northwestern
Pete Fiutak: Northwestern
John Kennedy: Northwestern
Jackson Langendorf: Northwestern*
Andrew Margolick: COMING
Jake Margolick: Northwestern
Doug Millen: Northwestern
Connor O’Gara: Northwestern
Johnny Rosenstein: Northwestern
Nick Shepkowski: Northwestern*
Clucko the Chicken: Michigan State
Consensus Pick: Northwestern
Auburn at Georgia
Game Preview and Prediction
Consensus Line: Georgia -20.5
Big Game Ben: Georgia
Andre Cherry: Georgia*
Riley Donald: Georgia
E: Georgia*
Pete Fiutak: Georgia*
John Kennedy: Georgia
Jackson Langendorf: Georgia*
Andrew Margolick: COMING
Jake Margolick: Georgia
Doug Millen: Georgia*
Connor O’Gara: Georgia
Johnny Rosenstein: Georgia*
Nick Shepkowski: Georgia
Clucko the Chicken: Georgia
Consensus Pick: Georgia
Alabama at Tennessee
Game Preview and Prediction
Consensus Line: Alabama -8.5
Big Game Ben: Alabama*
Andre Cherry: Alabama*
Riley Donald: Alabama
E: Tennessee
Pete Fiutak: Alabama
John Kennedy: Alabama
Jackson Langendorf: Alabama
Andrew Margolick: COMING
Jake Margolick: Alabama
Doug Millen: Alabama*
Connor O’Gara: Alabama*
Johnny Rosenstein: Alabama*
Nick Shepkowski: Alabama
Clucko the Chicken: Tennessee
Consensus Pick: Alabama*
Missouri at Ole Miss
Oct 10, 2026; Columbia, Missouri, USA; The Missouri Tigers cheerleaders perform agaiinst the Texas A&M Aggies during the second half of the game at Faurot Field at Memorial Stadium. Mandatory Credit: Denny Medley-Imagn Images
Game Preview and Prediction
Consensus Line: Ole Miss -6.5
Big Game Ben: Ole Miss*
Andre Cherry: Missouri
Riley Donald: Ole Miss
E: Ole Miss*
Pete Fiutak: Ole Miss
John Kennedy: Ole Miss
Jackson Langendorf: Ole Miss
Andrew Margolick: COMING
Jake Margolick: Ole Miss
Doug Millen: Ole Miss
Connor O’Gara: Ole Miss
Johnny Rosenstein: Missouri
Nick Shepkowski: Missouri
Clucko the Chicken: Missouri
Consensus Pick: Ole Miss
Arizona State at Texas Tech
Game Preview and Prediction
Consensus Line: Texas Tech -14.5
Big Game Ben: Texas Tech
Andre Cherry: Texas Tech
Riley Donald: Texas Tech
E: Texas Tech
Pete Fiutak: Texas Tech*
John Kennedy: Texas Tech
Jackson Langendorf: Texas Tech*
Andrew Margolick: COMING
Jake Margolick: Texas Tech*
Doug Millen: Texas Tech
Connor O’Gara: Texas Tech*
Johnny Rosenstein: Texas Tech*
Nick Shepkowski: Texas Tech
Clucko the Chicken: Texas Tech
Consensus Pick: Texas Tech
Penn State at Michigan
Game Preview and Prediction
Consensus Line: Michigna -6.5
Big Game Ben: Michigan*
Andre Cherry: Penn State
Riley Donald: Michigan*
E: Penn State
Pete Fiutak: Michigan*
John Kennedy: Michigan
Jackson Langendorf: Michigan
Andrew Margolick: COMING
Jake Margolick: Michigan*
Doug Millen: Michigan*
Connor O’Gara: Michigan*
Johnny Rosenstein: Michigan
Nick Shepkowski: Michigan*
Clucko the Chicken: Michigan
Consensus Pick: Michigan*
Florida State at Miami
Game Preview and Prediction
Consensus Line: Miami -21.5
Big Game Ben: Miami
Andre Cherry: Miami*
Riley Donald: Miami
E: Miami
Pete Fiutak: Miami
John Kennedy: Miami
Jackson Langendorf: Miami
Andrew Margolick: COMING
Jake Margolick: Miami
Doug Millen: Miami*
Connor O’Gara: Miami*
Johnny Rosenstein: Miami
Nick Shepkowski: Miami
Clucko the Chicken: Florida State
Consensus Pick: Miami
Notre Dame at BYU
Game Preview and Prediction
Consensus Line: Notre Dame -10.5
Big Game Ben: Notre Dame
Andre Cherry: Notre Dame
Riley Donald: Notre Dame
E: Notre Dame
Pete Fiutak: Notre Dame*
John Kennedy: Notre Dame
Jackson Langendorf: Notre Dame*
Andrew Margolick: COMING
Jake Margolick: Notre Dame*
Doug Millen: Notre Dame*
Connor O’Gara: Notre Dame*
Johnny Rosenstein: Notre Dame*
Nick Shepkowski: Notre Dame
Clucko the Chicken: BYU
Consensus Pick: Notre Dame*
Wisconsin at UCLA
Oct 3, 2026; Madison, Wisconsin, USA; Wisconsin Badgers head coach Luke Fickell prior to the game against the Michigan State Spartans at Camp Randall Stadium. Mandatory Credit: Jeff Hanisch-Imagn Images
Game Preview and Prediction
Consensus Line: UCLA -2.5
Big Game Ben: UCLA
Andre Cherry: Wisconsin
Riley Donald: UCLA
E: UCLA
Pete Fiutak: UCLA
John Kennedy: UCLA
Jackson Langendorf: UCLA
Andrew Margolick: COMING
Jake Margolick: Wisconsin
Doug Millen: UCLA
Connor O’Gara: UCLA
Johnny Rosenstein: UCLA*
Nick Shepkowski: UCLA
Clucko the Chicken: UCLA
Consensus Pick: UCLA
Kentucky at Oklahoma
Game Preview and Prediction
Consensus Line: Oklahoma -6.5
Big Game Ben: Oklahoma*
Andre Cherry: Kentucky
Riley Donald: Kentucky
E: Oklahoma*
Pete Fiutak: Oklahoma*
John Kennedy: Kentucky
Jackson Langendorf: Kentucky
Andrew Margolick: COMING
Jake Margolick: Oklahoma*
Doug Millen: Oklahoma*
Connor O’Gara: Oklahoma*
Johnny Rosenstein: Oklahoma*
Nick Shepkowski: Oklahoma*
Clucko the Chicken: Kentucky
Consensus Pick: Oklahoma*
Oklahoma State at Houston
Game Preview and Prediction
Consensus Line: Houston -4.5
Big Game Ben: Houston
Andre Cherry: Houston
Riley Donald: Oklahoma State
E: Houston
Pete Fiutak: Houston
John Kennedy: Houston
Jackson Langendorf: Oklahoma State
Andrew Margolick: COMING
Jake Margolick: Oklahoma State
Doug Millen: Houston*
Connor O’Gara: Houston
Johnny Rosenstein: Oklahoma State
Nick Shepkowski: Houston
Clucko the Chicken: Houston
Consensus Pick: Houston
Utah at Colorado
Game Preview and Prediction
Consensus Line: Utah -15.5
Big Game Ben: Utah
Andre Cherry: Utah
Riley Donald: Utah
E: Utah
Pete Fiutak: Utah
John Kennedy: Utah
Jackson Langendorf: Utah
Andrew Margolick: COMING
Jake Margolick: Utah
Doug Millen: Utah
Connor O’Gara: Utah
Johnny Rosenstein: Utah
Nick Shepkowski: Utah*
Clucko the Chicken: Colorado
Consensus Pick: Utah
Nebraska at Oregon
Game Preview and Prediction
Consensus Line: Oregon -7.5
Big Game Ben: Oregon*
Andre Cherry: Oregon
Riley Donald: Oregon
E: Oregon*
Pete Fiutak: Oregon
John Kennedy: Oregon
Jackson Langendorf: Oregon
Andrew Margolick: COMING
Jake Margolick: Oregon*
Doug Millen: Oregon*
Connor O’Gara: Oregon
Johnny Rosenstein: Oregon*
Nick Shepkowski: Oregon*
Clucko the Chicken: Nebraska
Consensus Pick: Oregon*
Expert Picks Results So Far
Big Game Ben
102-21 ATS: 65-68
Andre Cherry
SU: 100-33 ATS: 69-64
Riley Donald
SU: 106-27 ATS: 73-60
E
SU: 99-34 ATS: 66-67
Pete Fiutak
SU: 101-32 ATS: 74-59
John Kennedy
SU: 102-31 ATS: 68-65
Jackson Langendorf
SU: 93-40 ATS: 66-67
Andrew Margolick
SU: 98-35 ATS: 57-76
Jake Margolick
SU: 102-31 ATS: 70-63
Doug Millen
SU: 105-28 ATS: 72-61
Connor O’Gara
SU: 101-32 ATS: 70-63
Johnny Rosenstein
SU: 99-34 ATS: 60-73
Nick Shepkowski
SU: 98-35 ATS: 64-69
Clucko the Chicken
SU: 58-95 ATS: 60-73
Consensus Pick SU: 106-27 ATS: 69-64
Consensus line based on BetMGM, Caesars, DraftKings, and FanDuel. Game odds refresh periodically and are subject to change. If you or someone you know has a gambling problem and wants help, call 1-800-GAMBLER.